PDB 3h0b

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Overview

PDB Information

PDB	3H0B
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of aminoheterocycles as a novel beta-secretase inhibitor class: pH dependence on binding activity part 1. Stachel, S.J., Coburn, C.A., Rush, D., Jones, K.L., Zhu, H., Rajapakse, H., Graham, S.L., Simon, A., Katharine Holloway, M., Allison, T.J., Munshi, S.K., Espeseth, A.S., Zuck, P., Colussi, D., Wolfe, A., Pietrak, B.L., Lai, M.T., Vacca, J.P. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2009-04-08
Resolution	2.700
CATH Insert Date	16 Aug, 2009

PDB Images (10)

Image of CATH 3h0b

3h0b

PDB 3h0b

Image of CATH 3h0bA

3h0bA

PDB Chain 3h0bA

Image of CATH 3h0bB

3h0bB

PDB Chain 3h0bB

Image of CATH 3h0bC

3h0bC

PDB Chain 3h0bC

Image of CATH 3h0bA01

3h0bA01

CATH Domain 3h0bA01

Image of CATH 3h0bA02

3h0bA02

CATH Domain 3h0bA02

Image of CATH 3h0bB01

3h0bB01

CATH Domain 3h0bB01

Image of CATH 3h0bB02

3h0bB02

CATH Domain 3h0bB02

Image of CATH 3h0bC01

3h0bC01

CATH Domain 3h0bC01

Image of CATH 3h0bC02

3h0bC02

CATH Domain 3h0bC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	16 Aug, 2009	Chopped
B	16 Aug, 2009	Chopped
C	16 Aug, 2009	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3h0bA01	22 Jan, 2010	2.40.70.10	Assigned
3h0bA02	22 Jan, 2010	2.40.70.10	Assigned
3h0bB01	22 Jan, 2010	2.40.70.10	Assigned
3h0bB02	22 Jan, 2010	2.40.70.10	Assigned
3h0bC01	22 Jan, 2010	2.40.70.10	Assigned
3h0bC02	22 Jan, 2010	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1