PDB 3gzn

PDB Links
Overview

PDB Information

PDB	3GZN
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ. Brownell, J.E., Sintchak, M.D., Gavin, J.M., Liao, H., Bruzzese, F.J., Bump, N.J., Soucy, T.A., Milhollen, M.A., Yang, X., Burkhardt, A.L., Ma, J., Loke, H.K., Lingaraj, T., Wu, D., Hamman, K.B., Spelman, J.J., Cullis, C.A., Langston, S.P., Vyskocil, S., Sells, T.B., Mallender, W.D., Visiers, I., Li, P., Claiborne, C.F., Rolfe, M., Bolen, J.B., Dick, L.R. Mol.Cell
Header	Protein Binding/Ligase
Released	2009-04-07
Resolution	3.000
CATH Insert Date	07 Feb, 2010

PDB Images (19)

3gzn

PDB 3gzn

3gznA

PDB Chain 3gznA

3gznB

PDB Chain 3gznB

3gznC

PDB Chain 3gznC

3gznD

PDB Chain 3gznD

3gznI

PDB Chain 3gznI

3gznJ

PDB Chain 3gznJ

3gznA01

CATH Domain 3gznA01

3gznA02

CATH Domain 3gznA02

3gznB01

CATH Domain 3gznB01

3gznB02

CATH Domain 3gznB02

3gznB03

CATH Domain 3gznB03

3gznC01

CATH Domain 3gznC01

3gznC02

CATH Domain 3gznC02

3gznD01

CATH Domain 3gznD01

3gznD02

CATH Domain 3gznD02

3gznD03

CATH Domain 3gznD03

3gznI00

CATH Domain 3gznI00

3gznJ00

CATH Domain 3gznJ00

PDB Prints

PDB Chains (6)

Chain ID	Date inserted into CATH	CATH Status
A	08 Feb, 2010	Chopped
B	08 Feb, 2010	Chopped
C	08 Feb, 2010	Chopped
D	08 Feb, 2010	Chopped
I	08 Feb, 2010	Chopped
J	08 Feb, 2010	Chopped

CATH Domains (12)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3gznA01	09 Feb, 2010	3.40.50.720	Assigned
3gznA02	09 Feb, 2010		Holding pen
3gznB01	10 Feb, 2010	3.40.50.720	Assigned
3gznB02	10 Feb, 2010	1.10.10.520	Assigned
3gznB03	10 Feb, 2010	3.10.20.260	Assigned
3gznC01	10 Feb, 2010	3.40.50.720	Assigned
3gznC02	10 Feb, 2010		Holding pen
3gznD01	09 Feb, 2010	3.40.50.720	Assigned
3gznD02	09 Feb, 2010	1.10.10.520	Assigned
3gznD03	09 Feb, 2010	3.10.20.260	Assigned
3gznI00	28 Aug, 2013	3.10.20.90	Assigned
3gznJ00	28 Aug, 2013	3.10.20.90	Assigned

UniProtKB Entries (6)

Accession	Gene ID	Taxon	Description
Q15843	NEDD8_HUMAN	Homo sapiens	NEDD8
Q8TBC4	UBA3_HUMAN	Homo sapiens	NEDD8-activating enzyme E1 catalytic subunit
Q15843	NEDD8_HUMAN	Homo sapiens	NEDD8
Q8TBC4	UBA3_HUMAN	Homo sapiens	NEDD8-activating enzyme E1 catalytic subunit
Q13564	ULA1_HUMAN	Homo sapiens	NEDD8-activating enzyme E1 regulatory subunit
Q13564	ULA1_HUMAN	Homo sapiens	NEDD8-activating enzyme E1 regulatory subunit