PDB 3gn1

PDB Links
Overview

PDB Information

PDB	3GN1
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	Trypanosoma brucei brucei
Primary Citation	One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening. Mpamhanga, C.P., Spinks, D., Tulloch, L.B., Shanks, E.J., Robinson, D.A., Collie, I.T., Fairlamb, A.H., Wyatt, P.G., Frearson, J.A., Hunter, W.N., Gilbert, I.H., Brenk, R. J.Med.Chem.
Header	Oxidoreductase
Released	2009-03-16
Resolution	2.000
CATH Insert Date	31 Dec, 2009

PDB Images (9)

Image of CATH 3gn1

3gn1

PDB 3gn1

Image of CATH 3gn1A

3gn1A

PDB Chain 3gn1A

Image of CATH 3gn1B

3gn1B

PDB Chain 3gn1B

Image of CATH 3gn1C

3gn1C

PDB Chain 3gn1C

Image of CATH 3gn1D

3gn1D

PDB Chain 3gn1D

Image of CATH 3gn1A00

3gn1A00

CATH Domain 3gn1A00

Image of CATH 3gn1B00

3gn1B00

CATH Domain 3gn1B00

Image of CATH 3gn1C00

3gn1C00

CATH Domain 3gn1C00

Image of CATH 3gn1D00

3gn1D00

CATH Domain 3gn1D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	31 Dec, 2009	Chopped
B	31 Dec, 2009	Chopped
C	31 Dec, 2009	Chopped
D	31 Dec, 2009	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3gn1A00	09 Jan, 2010	3.40.50.720	Assigned
3gn1B00	09 Jan, 2010	3.40.50.720	Assigned
3gn1C00	09 Jan, 2010	3.40.50.720	Assigned
3gn1D00	08 Jan, 2010	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O76290	O76290_TRYBB	Trypanosoma brucei brucei	Pteridine reductase
O76290	O76290_TRYBB	Trypanosoma brucei brucei	Pteridine reductase
O76290	O76290_TRYBB	Trypanosoma brucei brucei	Pteridine reductase
O76290	O76290_TRYBB	Trypanosoma brucei brucei	Pteridine reductase