PDB 3frj

PDB Links
Overview

PDB Information

PDB	3FRJ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and optimization of piperidyl benzamide derivatives as a novel class of 11beta-HSD1 inhibitors. Rew, Y., McMinn, D.L., Wang, Z., He, X., Hungate, R.W., Jaen, J.C., Sudom, A., Sun, D., Tu, H., Ursu, S., Villemure, E., Walker, N.P., Yan, X., Ye, Q., Powers, J.P. Bioorg.Med.Chem.Lett.
Header	Oxidoreductase
Released	2009-01-08
Resolution	2.300
CATH Insert Date	16 Aug, 2009

PDB Images (5)

Image of CATH 3frj

3frj

PDB 3frj

Image of CATH 3frjA

3frjA

PDB Chain 3frjA

Image of CATH 3frjB

3frjB

PDB Chain 3frjB

Image of CATH 3frjA00

3frjA00

CATH Domain 3frjA00

Image of CATH 3frjB00

3frjB00

CATH Domain 3frjB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	16 Aug, 2009	Chopped
B	16 Aug, 2009	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3frjA00	07 Dec, 2009	3.40.50.720	Assigned
3frjB00	07 Dec, 2009	3.40.50.720	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1