PDB 3fl8
PDB Information
| PDB | 3FL8 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Bacillus anthracis |
| Primary Citation | Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity.
Antimicrob.Agents Chemother.
|
| Header | Oxidoreductase |
| Released | 2008-12-18 |
| Resolution | 2.290 |
| CATH Insert Date | 16 Aug, 2009 |
PDB Images (17)
3fl8
PDB 3fl8
3fl8A
PDB Chain 3fl8A
3fl8B
PDB Chain 3fl8B
3fl8C
PDB Chain 3fl8C
3fl8D
PDB Chain 3fl8D
3fl8E
PDB Chain 3fl8E
3fl8F
PDB Chain 3fl8F
3fl8G
PDB Chain 3fl8G
3fl8H
PDB Chain 3fl8H
3fl8A00
CATH Domain 3fl8A00
3fl8B00
CATH Domain 3fl8B00
3fl8C00
CATH Domain 3fl8C00
3fl8D00
CATH Domain 3fl8D00
3fl8E00
CATH Domain 3fl8E00
3fl8F00
CATH Domain 3fl8F00
3fl8G00
CATH Domain 3fl8G00
3fl8H00
CATH Domain 3fl8H00
PDB Prints
PDB Chains (8)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Aug, 2009 | Chopped |
| B | 16 Aug, 2009 | Chopped |
| C | 16 Aug, 2009 | Chopped |
| D | 16 Aug, 2009 | Chopped |
| E | 16 Aug, 2009 | Chopped |
| F | 16 Aug, 2009 | Chopped |
| G | 16 Aug, 2009 | Chopped |
| H | 16 Aug, 2009 | Chopped |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3fl8A00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl8B00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl8C00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl8D00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl8E00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl8F00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl8G00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl8H00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
UniProtKB Entries (8)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |