PDB 3fco

PDB Information

PDB3FCO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Optimization of novel di-substituted cyclohexylbenzamide derivatives as potent 11 beta-HSD1 inhibitors.
McMinn, D.L., Rew, Y., Sudom, A., Caille, S., Degraffenreid, M., He, X., Hungate, R., Jiang, B., Jaen, J., Julian, L.D., Kaizerman, J., Novak, P., Sun, D., Tu, H., Ursu, S., Walker, N.P., Yan, X., Ye, Q., Wang, Z., Powers, J.P.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2008-11-21
Resolution2.650
CATH Insert Date03 Dec, 2009

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Dec, 2009 Chopped
B 03 Dec, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3fcoA00 06 Dec, 2009 3.40.50.720 Assigned
3fcoB00 05 Dec, 2009 3.40.50.720 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1