PDB 3exo

PDB Information

PDB3EXO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement.
Steele, T.G., Hills, I.D., Nomland, A.A., de Leon, P., Allison, T., McGaughey, G., Colussi, D., Tugusheva, K., Haugabook, S.J., Espeseth, A.S., Zuck, P., Graham, S.L., Stachel, S.J.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2008-10-16
Resolution2.100
CATH Insert Date05 Feb, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Feb, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3exoA01 18 Feb, 2009 2.40.70.10 Assigned
3exoA02 18 Feb, 2009 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1