PDB 3eqb

PDB Information

PDB3EQB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles-O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase).
Warmus, J.S., Flamme, C., Zhang, L.Y., Barrett, S., Bridges, A., Chen, H., Gowan, R., Kaufman, M., Sebolt-Leopold, J., Leopold, W., Merriman, R., Ohren, J., Pavlovsky, A., Przybranowski, S., Tecle, H., Valik, H., Whitehead, C., Zhang, E.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2008-09-30
Resolution2.620
CATH Insert Date13 Nov, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 13 Nov, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3eqbA01 14 Nov, 2008 3.30.200.20 Assigned
3eqbA02 14 Nov, 2008 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1