PDB 3eob
PDB Information
| PDB | 3EOB |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Proc.Natl.Acad.Sci.USA
|
| Header | Immune System/Cell Adhesion |
| Released | 2008-09-26 |
| Resolution | 3.600 |
| CATH Insert Date | 16 Aug, 2009 |
PDB Images (17)
3eob
PDB 3eob
3eobA
PDB Chain 3eobA
3eobB
PDB Chain 3eobB
3eobH
PDB Chain 3eobH
3eobI
PDB Chain 3eobI
3eobJ
PDB Chain 3eobJ
3eobL
PDB Chain 3eobL
3eobA01
CATH Domain 3eobA01
3eobA02
CATH Domain 3eobA02
3eobB01
CATH Domain 3eobB01
3eobB02
CATH Domain 3eobB02
3eobH01
CATH Domain 3eobH01
3eobH02
CATH Domain 3eobH02
3eobI00
CATH Domain 3eobI00
3eobJ00
CATH Domain 3eobJ00
3eobL01
CATH Domain 3eobL01
3eobL02
CATH Domain 3eobL02
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Aug, 2009 | Chopped |
| B | 16 Aug, 2009 | Chopped |
| H | 16 Aug, 2009 | Chopped |
| I | 16 Aug, 2009 | Chopped |
| J | 16 Aug, 2009 | Chopped |
| L | 16 Aug, 2009 | Chopped |
CATH Domains (10)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3eobA01 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eobA02 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eobB01 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eobB02 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eobH01 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eobH02 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eobI00 | 29 Sep, 2009 | 3.40.50.410 | Assigned |
| 3eobJ00 | 29 Sep, 2009 | 3.40.50.410 | Assigned |
| 3eobL01 | 18 May, 2010 | 2.60.40.10 | Assigned |
| 3eobL02 | 18 May, 2010 | 2.60.40.10 | Assigned |
UniProtKB Entries (2)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P20701 | ITAL_HUMAN | Homo sapiens | Integrin alpha-L |
| P20701 | ITAL_HUMAN | Homo sapiens | Integrin alpha-L |
