PDB 3emg

PDB Information

PDB3EMG
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK).
Farmer, L.J., Bemis, G., Britt, S.D., Cochran, J., Connors, M., Harrington, E.M., Hoock, T., Markland, W., Nanthakumar, S., Taslimi, P., Ter Haar, E., Wang, J., Zhaveri, D., Salituro, F.G.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2008-09-24
Resolution2.600
CATH Insert Date07 Dec, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Dec, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3emgA01 31 Mar, 2009 3.30.200.20 Assigned
3emgA02 31 Mar, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK