PDB Information

PDB3ELJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity.
Chamberlain, S.D., Redman, A.M., Wilson, J.W., Deanda, F., Shotwell, J.B., Gerding, R., Lei, H., Yang, B., Stevens, K.L., Hassell, A.M., Shewchuk, L.M., Leesnitzer, M.A., Smith, J.L., Sabbatini, P., Atkins, C., Groy, A., Rowand, J.L., Kumar, R., Mook, R.A., Moorthy, G., Patnaik, S.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2008-09-22
Resolution1.800
CATH Insert Date01 Jan, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 01 Jan, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3eljA01 07 Jan, 2009 3.30.200.20 Assigned
3eljA02 07 Jan, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P45983 MK08_HUMAN Homo sapiens Mitogen-activated protein kinase 8