PDB 3efw

PDB Links
Overview

PDB Information

PDB	3EFW
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase. Cee, V.J., Cheng, A.C., Romero, K., Bellon, S., Mohr, C., Whittington, D.A., Bak, A., Bready, J., Caenepeel, S., Coxon, A., Deak, H.L., Fretland, J., Gu, Y., Hodous, B.L., Huang, X., Kim, J.L., Lin, J., Long, A.M., Nguyen, H., Olivieri, P.R., Patel, V.F., Wang, L., Zhou, Y., Hughes, P., Geuns-Meyer, S. Bioorg.Med.Chem.Lett.
Header	Transferase/Inhibitor
Released	2008-09-10
Resolution	2.290
CATH Insert Date	25 Dec, 2008

PDB Images (7)

Image of CATH 3efw

3efw

PDB 3efw

Image of CATH 3efwA

3efwA

PDB Chain 3efwA

Image of CATH 3efwB

3efwB

PDB Chain 3efwB

Image of CATH 3efwA01

3efwA01

CATH Domain 3efwA01

Image of CATH 3efwA02

3efwA02

CATH Domain 3efwA02

Image of CATH 3efwB01

3efwB01

CATH Domain 3efwB01

Image of CATH 3efwB02

3efwB02

CATH Domain 3efwB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	25 Dec, 2008	Chopped
B	25 Dec, 2008	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3efwA01	07 Jan, 2009	3.30.200.20	Assigned
3efwA02	07 Jan, 2009	1.10.510.10	Assigned
3efwB01	07 Jan, 2009	3.30.200.20	Assigned
3efwB02	07 Jan, 2009	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A