PDB Information

PDB3E30
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceRattus norvegicus
Primary Citation
Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.
Hast, M.A., Fletcher, S., Cummings, C.G., Pusateri, E.E., Blaskovich, M.A., Rivas, K., Gelb, M.H., Van Voorhis, W.C., Sebti, S.M., Hamilton, A.D., Beese, L.S.
Chem.Biol.
HeaderTransferase
Released2008-08-06
Resolution2.450
CATH Insert Date12 Mar, 2009

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 12 Mar, 2009 Chopped
B 12 Mar, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3e30A00 13 Mar, 2009 1.25.40.120 Assigned
3e30B00 13 Mar, 2009 1.50.10.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q04631 FNTA_RAT Rattus norvegicus Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Q02293 FNTB_RAT Rattus norvegicus Protein farnesyltransferase subunit beta