PDB 3dm6

PDB Links
Overview

PDB Information

PDB	3DM6
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues Back, M., Nyhlen, J., Kvarnstrom, I., Appelgren, S., Borkakoti, N., Jansson, K., Lindberg, J., Nystrom, S., Hallberg, A., Rosenquist, S., Samuelsson, B. Bioorg.Med.Chem.
Header	Hydrolase
Released	2008-06-30
Resolution	2.600
CATH Insert Date	18 Dec, 2008

PDB Images (10)

Image of CATH 3dm6

3dm6

PDB 3dm6

Image of CATH 3dm6A

3dm6A

PDB Chain 3dm6A

Image of CATH 3dm6B

3dm6B

PDB Chain 3dm6B

Image of CATH 3dm6C

3dm6C

PDB Chain 3dm6C

Image of CATH 3dm6A01

3dm6A01

CATH Domain 3dm6A01

Image of CATH 3dm6A02

3dm6A02

CATH Domain 3dm6A02

Image of CATH 3dm6B01

3dm6B01

CATH Domain 3dm6B01

Image of CATH 3dm6B02

3dm6B02

CATH Domain 3dm6B02

Image of CATH 3dm6C01

3dm6C01

CATH Domain 3dm6C01

Image of CATH 3dm6C02

3dm6C02

CATH Domain 3dm6C02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	18 Dec, 2008	Chopped
B	18 Dec, 2008	Chopped
C	18 Dec, 2008	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3dm6A01	19 Dec, 2008	2.40.70.10	Assigned
3dm6A02	19 Dec, 2008	2.40.70.10	Assigned
3dm6B01	19 Dec, 2008	2.40.70.10	Assigned
3dm6B02	19 Dec, 2008	2.40.70.10	Assigned
3dm6C01	19 Dec, 2008	2.40.70.10	Assigned
3dm6C02	19 Dec, 2008	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1