PDB Information

PDB3D7V
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation.
Lee, E.F., Czabotar, P.E., van Delft, M.F., Michalak, E.M., Boyle, M.J., Willis, S.N., Puthalakath, H., Bouillet, P., Colman, P.M., Huang, D.C.S., Fairlie, W.D.
J.Cell Biol.
HeaderApoptosis
Released2008-05-22
Resolution2.030
CATH Insert Date23 Jul, 2008

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3d7vA01 23 Apr, 2009 1.10.437.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
P97287 MCL1_MOUSE Mus musculus Induced myeloid leukemia cell differentiation protein Mcl-1 homolog