PDB 3d3e

PDB Links
Overview

PDB Information

PDB	3D3E
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model Julian, L.D., Wang, Z., Bostick, T., Caille, S., Choi, R., Degraffenreid, M., Di, Y., He, X., Hungate, R.W., Jaen, J.C., Liu, J., Monshouwer, M., McMinn, D., Rew, Y., Sudom, A., Sun, D., Tu, H., Ursu, S., Walker, N., Yan, X., Ye, Q., Powers, J.P. J.Med.Chem.
Header	Oxidoreductase
Released	2008-05-09
Resolution	2.600
CATH Insert Date	23 Jul, 2008

PDB Images (9)

Image of CATH 3d3e

3d3e

PDB 3d3e

Image of CATH 3d3eA

3d3eA

PDB Chain 3d3eA

Image of CATH 3d3eB

3d3eB

PDB Chain 3d3eB

Image of CATH 3d3eC

3d3eC

PDB Chain 3d3eC

Image of CATH 3d3eD

3d3eD

PDB Chain 3d3eD

Image of CATH 3d3eA00

3d3eA00

CATH Domain 3d3eA00

Image of CATH 3d3eB00

3d3eB00

CATH Domain 3d3eB00

Image of CATH 3d3eC00

3d3eC00

CATH Domain 3d3eC00

Image of CATH 3d3eD00

3d3eD00

CATH Domain 3d3eD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	24 Jul, 2008	Chopped
B	24 Jul, 2008	Chopped
C	24 Jul, 2008	Chopped
D	24 Jul, 2008	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3d3eA00	05 Dec, 2008	3.40.50.720	Assigned
3d3eB00	05 Dec, 2008	3.40.50.720	Assigned
3d3eC00	05 Dec, 2008	3.40.50.720	Assigned
3d3eD00	05 Dec, 2008	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1