Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase.
Heerding, D.A., Rhodes, N., Leber, J.D., Clark, T.J., Keenan, R.M., Lafrance, L.V., Li, M., Safonov, I.G., Takata, D.T., Venslavsky, J.W., Yamashita, D.S., Choudhry, A.E., Copeland, R.A., Lai, Z., Schaber, M.D., Tummino, P.J., Strum, S.L., Wood, E.R., Duckett, D.R., Eberwein, D., Knick, V.B., Lansing, T.J., McConnell, R.T., Zhang, S., Minthorn, E.A., Concha, N.O., Warren, G.L., Kumar, R.
J.Med.Chem.