PDB 3cwj

PDB Links
Overview

PDB Information

PDB	3CWJ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus
Primary Citation	4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase Ellis, D.A., Blazel, J.K., Webber, S.E., Tran, C.V., Dragovich, P.S., Sun, Z., Ruebsam, F., McGuire, H.M., Xiang, A.X., Zhao, J., Li, L.S., Zhou, Y., Han, Q., Kissinger, C.R., Showalter, R.E., Lardy, M., Shah, A.M., Tsan, M., Patel, R., LeBrun, L.A., Kamran, R., Bartkowski, D.M., Nolan, T.G., Norris, D.A., Sergeeva, M.V., Kirkovsky, L. Bioorg.Med.Chem.Lett.
Header	Transferase, Viral Protein
Released	2008-04-21
Resolution	2.400
CATH Insert Date	16 Aug, 2009

PDB Images (11)

Image of CATH 3cwj

3cwj

PDB 3cwj

Image of CATH 3cwjA

3cwjA

PDB Chain 3cwjA

Image of CATH 3cwjB

3cwjB

PDB Chain 3cwjB

Image of CATH 3cwjA01

3cwjA01

CATH Domain 3cwjA01

Image of CATH 3cwjA02

3cwjA02

CATH Domain 3cwjA02

Image of CATH 3cwjA03

3cwjA03

CATH Domain 3cwjA03

Image of CATH 3cwjA04

3cwjA04

CATH Domain 3cwjA04

Image of CATH 3cwjB01

3cwjB01

CATH Domain 3cwjB01

Image of CATH 3cwjB02

3cwjB02

CATH Domain 3cwjB02

Image of CATH 3cwjB03

3cwjB03

CATH Domain 3cwjB03

Image of CATH 3cwjB04

3cwjB04

CATH Domain 3cwjB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	16 Aug, 2009	Chopped
B	16 Aug, 2009	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3cwjA01	03 Oct, 2013		Holding pen
3cwjA02	03 Oct, 2013		Holding pen
3cwjA03	03 Oct, 2013	3.30.70.270	Assigned
3cwjA04	03 Oct, 2013		Holding pen
3cwjB01	03 Oct, 2013		Holding pen
3cwjB02	03 Oct, 2013		Holding pen
3cwjB03	03 Oct, 2013	3.30.70.270	Assigned
3cwjB04	03 Oct, 2013		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein