PDB Information

PDB3CS7
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Achieving structural diversity using the perpendicular conformation of alpha-substituted phenylcyclopropanes to mimic the bioactive conformation of ortho-substituted biphenyl P4 moieties: discovery of novel, highly potent inhibitors of Factor Xa.
Qiao, J.X., Cheney, D.L., Alexander, R.S., Smallwood, A.M., King, S.R., He, K., Rendina, A.R., Luettgen, J.M., Knabb, R.M., Wexler, R.R., Lam, P.Y.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2008-04-09
Resolution2.200
CATH Insert Date23 Jul, 2008

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
L 24 Jul, 2008 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
3cs7A01 26 Jul, 2008 2.40.10.10 Assigned
3cs7A02 26 Jul, 2008 2.40.10.10 Assigned
3cs7L00 25 Jul, 2008 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X