PDB 3coh

PDB Links
Overview

PDB Information

PDB	3COH
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability. Rawson, T.E., Ruth, M., Blackwood, E., Burdick, D., Corson, L., Dotson, J., Drummond, J., Fields, C., Georges, G.J., Goller, B., Halladay, J., Hunsaker, T., Kleinheinz, T., Krell, H.W., Li, J., Liang, J., Limberg, A., McNutt, A., Moffat, J., Phillips, G., Ran, Y., Safina, B., Ultsch, M., Walker, L., Wiesmann, C., Zhang, B., Zhou, A., Zhu, B.Y., Ruger, P., Cochran, A.G. J.Med.Chem.
Header	Transferase
Released	2008-03-28
Resolution	2.700
CATH Insert Date	19 Feb, 2009

PDB Images (7)

Image of CATH 3coh

3coh

PDB 3coh

Image of CATH 3cohA

3cohA

PDB Chain 3cohA

Image of CATH 3cohB

3cohB

PDB Chain 3cohB

Image of CATH 3cohA01

3cohA01

CATH Domain 3cohA01

Image of CATH 3cohA02

3cohA02

CATH Domain 3cohA02

Image of CATH 3cohB01

3cohB01

CATH Domain 3cohB01

Image of CATH 3cohB02

3cohB02

CATH Domain 3cohB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	19 Feb, 2009	Chopped
B	19 Feb, 2009	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3cohA01	03 Mar, 2009	3.30.200.20	Assigned
3cohA02	03 Mar, 2009	1.10.510.10	Assigned
3cohB01	03 Mar, 2009	3.30.200.20	Assigned
3cohB02	03 Mar, 2009	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A