PDB Information

PDB3CLB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceTrypanosoma cruzi
Primary Citation
Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
Schormann, N., Senkovich, O., Walker, K., Wright, D.L., Anderson, A.C., Rosowsky, A., Ananthan, S., Shinkre, B., Velu, S., Chattopadhyay, D.
Proteins
HeaderOxidoreductase, Transferase
Released2008-03-18
Resolution3.000
CATH Insert Date08 Jan, 2009

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Jan, 2009 Chopped
B 08 Jan, 2009 Chopped
C 08 Jan, 2009 Chopped
D 08 Jan, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3clbA01 10 May, 2013 3.40.430.10 Assigned
3clbA02 10 May, 2013 3.30.572.10 Assigned
3clbB01 10 May, 2013 3.40.430.10 Assigned
3clbB02 10 May, 2013 3.30.572.10 Assigned
3clbC01 10 May, 2013 3.40.430.10 Assigned
3clbC02 10 May, 2013 3.30.572.10 Assigned
3clbD01 10 May, 2013 3.40.430.10 Assigned
3clbD02 10 May, 2013 3.30.572.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase
Q27793 DRTS_TRYCR Trypanosoma cruzi Bifunctional dihydrofolate reductase-thymidylate synthase