PDB Information

PDB3CJG
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor.
Harris, P.A., Boloor, A., Cheung, M., Kumar, R., Crosby, R.M., Davis-Ward, R.G., Epperly, A.H., Hinkle, K.W., Hunter, R.N., Johnson, J.H., Knick, V.B., Laudeman, C.P., Luttrell, D.K., Mook, R.A., Nolte, R.T., Rudolph, S.K., Szewczyk, J.R., Truesdale, A.T., Veal, J.M., Wang, L., Stafford, J.A.
J.Med.Chem.
HeaderTransferase
Released2008-03-12
Resolution2.250
CATH Insert Date09 Oct, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 09 Oct, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3cjgA01 11 Oct, 2008 3.30.200.20 Assigned
3cjgA02 11 Oct, 2008 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P35968 VGFR2_HUMAN Homo sapiens Vascular endothelial growth factor receptor 2