PDB 3ch6

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Overview

PDB Information

PDB	3CH6
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 Wang, H., Ruan, Z., Li, J.J., Simpkins, L.M., Smirk, R.A., Wu, S.C., Hutchins, R.D., Nirschl, D.S., Van Kirk, K., Cooper, C.B., Sutton, J.C., Ma, Z., Golla, R., Seethala, R., Salyan, M.E., Nayeem, A., Krystek, S.R., Sheriff, S., Camac, D.M., Morin, P.E., Carpenter, B., Robl, J.A., Zahler, R., Gordon, D.A., Hamann, L.G. Bioorg.Med.Chem.Lett.
Header	Oxidoreductase
Released	2008-03-07
Resolution	2.350
CATH Insert Date	23 Jul, 2008

PDB Images (9)

Image of CATH 3ch6

3ch6

PDB 3ch6

Image of CATH 3ch6A

3ch6A

PDB Chain 3ch6A

Image of CATH 3ch6B

3ch6B

PDB Chain 3ch6B

Image of CATH 3ch6D

3ch6D

PDB Chain 3ch6D

Image of CATH 3ch6E

3ch6E

PDB Chain 3ch6E

Image of CATH 3ch6A00

3ch6A00

CATH Domain 3ch6A00

Image of CATH 3ch6B01

3ch6B01

CATH Domain 3ch6B01

Image of CATH 3ch6D01

3ch6D01

CATH Domain 3ch6D01

Image of CATH 3ch6E00

3ch6E00

CATH Domain 3ch6E00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	24 Jul, 2008	Chopped
B	24 Jul, 2008	Chopped
D	24 Jul, 2008	Chopped
E	24 Jul, 2008	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3ch6A00	05 Dec, 2008	3.40.50.720	Assigned
3ch6B01	05 Dec, 2008	3.40.50.720	Assigned
3ch6D01	05 Dec, 2008	3.40.50.720	Assigned
3ch6E00	05 Dec, 2008	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1