PDB 3ccz

PDB Information

PDB3CCZ
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase.
Sarver, R.W., Bills, E., Bolton, G., Bratton, L.D., Caspers, N.L., Dunbar, J.B., Harris, M.S., Hutchings, R.H., Kennedy, R.M., Larsen, S.D., Pavlovsky, A., Pfefferkorn, J.A., Bainbridge, G.
J.Med.Chem.
HeaderOxidoreductase
Released2008-02-26
Resolution1.700
CATH Insert Date23 Jul, 2008

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped
C 24 Jul, 2008 Chopped
D 24 Jul, 2008 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
3cczA01 26 Jul, 2008 1.10.3270.10 Assigned
3cczA02 26 Jul, 2008 3.90.770.10 Assigned
3cczA03 26 Jul, 2008 3.30.70.420 Assigned
3cczB01 26 Jul, 2008 1.10.3270.10 Assigned
3cczB02 26 Jul, 2008 3.90.770.10 Assigned
3cczB03 26 Jul, 2008 3.30.70.420 Assigned
3cczC01 26 Jul, 2008 1.10.3270.10 Assigned
3cczC02 26 Jul, 2008 3.90.770.10 Assigned
3cczC03 26 Jul, 2008 3.30.70.420 Assigned
3cczD01 26 Jul, 2008 1.10.3270.10 Assigned
3cczD02 26 Jul, 2008 3.90.770.10 Assigned
3cczD03 26 Jul, 2008 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase