PDB 3c6t

PDB Information

PDB3C6T
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHIV-1 M:B_HXB2R
Primary Citation
The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations.
Tucker, T.J., Saggar, S., Sisko, J.T., Tynebor, R.M., Williams, T.M., Felock, P.J., Flynn, J.A., Lai, M.T., Liang, Y., McGaughey, G., Liu, M., Miller, M., Moyer, G., Munshi, V., Perlow-Poehnelt, R., Prasad, S., Sanchez, R., Torrent, M., Vacca, J.P., Wan, B.L., Yan, Y.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2008-02-05
Resolution2.700
CATH Insert Date27 Apr, 2008

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 27 Apr, 2008 Chopped
B 27 Apr, 2008 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
3c6tA01 28 Apr, 2008 3.10.10.10 Assigned
3c6tA02 28 Apr, 2008 3.30.70.270 Assigned
3c6tA03 28 Apr, 2008 3.30.70.270 Assigned
3c6tA04 28 Apr, 2008 3.30.70.270 Assigned
3c6tA05 28 Apr, 2008 3.30.420.10 Assigned
3c6tB01 28 Apr, 2008 3.10.10.10 Assigned
3c6tB02 28 Apr, 2008 3.30.70.270 Assigned
3c6tB03 28 Apr, 2008 3.30.70.270 Assigned
3c6tB04 28 Apr, 2008 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein
P04585 POL_HV1H2 HIV-1 M:B_HXB2R Gag-Pol polyprotein
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