PDB 3bsc

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Overview

PDB Information

PDB	3BSC
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus (isolate BK)
Primary Citation	Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine. Zhou, Y., Webber, S.E., Murphy, D.E., Li, L.S., Dragovich, P.S., Tran, C.V., Sun, Z., Ruebsam, F., Shah, A.M., Tsan, M., Showalter, R.E., Patel, R., Li, B., Zhao, Q., Han, Q., Hermann, T., Kissinger, C.R., Lebrun, L., Sergeeva, M.V., Kirkovsky, L. Bioorg.Med.Chem.Lett.
Header	Transferase
Released	2007-12-23
Resolution	2.650
CATH Insert Date	25 Dec, 2008

PDB Images (11)

Image of CATH 3bsc

3bsc

PDB 3bsc

Image of CATH 3bscA

3bscA

PDB Chain 3bscA

Image of CATH 3bscB

3bscB

PDB Chain 3bscB

Image of CATH 3bscA01

3bscA01

CATH Domain 3bscA01

Image of CATH 3bscA02

3bscA02

CATH Domain 3bscA02

Image of CATH 3bscA03

3bscA03

CATH Domain 3bscA03

Image of CATH 3bscA04

3bscA04

CATH Domain 3bscA04

Image of CATH 3bscB01

3bscB01

CATH Domain 3bscB01

Image of CATH 3bscB02

3bscB02

CATH Domain 3bscB02

Image of CATH 3bscB03

3bscB03

CATH Domain 3bscB03

Image of CATH 3bscB04

3bscB04

CATH Domain 3bscB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	25 Dec, 2008	Chopped
B	25 Dec, 2008	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3bscA01	03 Oct, 2013		Holding pen
3bscA02	03 Oct, 2013		Holding pen
3bscA03	03 Oct, 2013	3.30.70.270	Assigned
3bscA04	03 Oct, 2013		Holding pen
3bscB01	03 Oct, 2013		Holding pen
3bscB02	03 Oct, 2013		Holding pen
3bscB03	03 Oct, 2013	3.30.70.270	Assigned
3bscB04	03 Oct, 2013		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein