PDB 3b2u

PDB Information

PDB3B2U
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8.
Li, S., Kussie, P., Ferguson, K.M.
Structure
HeaderImmune System/Transferase
Released2007-10-19
Resolution2.580
CATH Insert Date21 Feb, 2008

PDB Images (65)

PDB Prints

PDB Chains (24)

Chain ID Date inserted into CATH CATH Status
A 21 Feb, 2008 Chopped
B 21 Feb, 2008 Chopped
C 21 Feb, 2008 Chopped
D 21 Feb, 2008 Chopped
E 21 Feb, 2008 Chopped
F 21 Feb, 2008 Chopped
G 21 Feb, 2008 Chopped
H 21 Feb, 2008 Chopped
I 21 Feb, 2008 Chopped
J 21 Feb, 2008 Chopped
K 21 Feb, 2008 Chopped
L 21 Feb, 2008 Chopped
M 21 Feb, 2008 Chopped
N 21 Feb, 2008 Chopped
O 21 Feb, 2008 Chopped
P 21 Feb, 2008 Chopped
Q 21 Feb, 2008 Chopped
R 21 Feb, 2008 Chopped
S 21 Feb, 2008 Chopped
T 21 Feb, 2008 Chopped
U 21 Feb, 2008 Chopped
V 21 Feb, 2008 Chopped
W 21 Feb, 2008 Chopped
X 21 Feb, 2008 Chopped

CATH Domains (40)

Domain ID Date inserted into CATH Superfamily CATH Status
3b2uA00 22 Sep, 2008 3.80.20.20 Assigned
3b2uB00 22 Sep, 2008 3.80.20.20 Assigned
3b2uC01 26 Oct, 2009 2.60.40.10 Assigned
3b2uC02 26 Oct, 2009 2.60.40.10 Assigned
3b2uD01 05 Dec, 2008 2.60.40.10 Assigned
3b2uD02 05 Dec, 2008 2.60.40.10 Assigned
3b2uE00 22 Sep, 2008 3.80.20.20 Assigned
3b2uF01 26 Oct, 2009 2.60.40.10 Assigned
3b2uF02 26 Oct, 2009 2.60.40.10 Assigned
3b2uG01 05 Dec, 2008 2.60.40.10 Assigned
3b2uG02 05 Dec, 2008 2.60.40.10 Assigned
3b2uH01 26 Oct, 2009 2.60.40.10 Assigned
3b2uH02 26 Oct, 2009 2.60.40.10 Assigned
3b2uI00 22 Sep, 2008 3.80.20.20 Assigned
3b2uJ01 26 Oct, 2009 2.60.40.10 Assigned
3b2uJ02 26 Oct, 2009 2.60.40.10 Assigned
3b2uK01 05 Dec, 2008 2.60.40.10 Assigned
3b2uK02 05 Dec, 2008 2.60.40.10 Assigned
3b2uL01 05 Dec, 2008 2.60.40.10 Assigned
3b2uL02 05 Dec, 2008 2.60.40.10 Assigned
3b2uM00 22 Sep, 2008 3.80.20.20 Assigned
3b2uN01 26 Oct, 2009 2.60.40.10 Assigned
3b2uN02 26 Oct, 2009 2.60.40.10 Assigned
3b2uO01 05 Dec, 2008 2.60.40.10 Assigned
3b2uO02 05 Dec, 2008 2.60.40.10 Assigned
3b2uP00 22 Sep, 2008 3.80.20.20 Assigned
3b2uQ01 26 Oct, 2009 2.60.40.10 Assigned
3b2uQ02 26 Oct, 2009 2.60.40.10 Assigned
3b2uR01 05 Dec, 2008 2.60.40.10 Assigned
3b2uR02 05 Dec, 2008 2.60.40.10 Assigned
3b2uS00 22 Sep, 2008 3.80.20.20 Assigned
3b2uT01 26 Oct, 2009 2.60.40.10 Assigned
3b2uT02 26 Oct, 2009 2.60.40.10 Assigned
3b2uU01 05 Dec, 2008 2.60.40.10 Assigned
3b2uU02 05 Dec, 2008 2.60.40.10 Assigned
3b2uV00 22 Sep, 2008 3.80.20.20 Assigned
3b2uW01 26 Oct, 2009 2.60.40.10 Assigned
3b2uW02 26 Oct, 2009 2.60.40.10 Assigned
3b2uX01 05 Dec, 2008 2.60.40.10 Assigned
3b2uX02 05 Dec, 2008 2.60.40.10 Assigned

UniProtKB Entries (11)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
Q6GMX6 Q6GMX6_HUMAN Homo sapiens IGH@ protein
Q6GMX6 Q6GMX6_HUMAN Homo sapiens IGH@ protein
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
Q6GMX6 Q6GMX6_HUMAN Homo sapiens IGH@ protein
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
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