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PDB 2zec

PDB Information

PDB2ZEC
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives
Costanzo, M.J., Yabut, S.C., Zhang, H.-C., White, K.B., de Garavilla, L., Wang, Y., Minor, L.K., Tounge, B.A., Barnakov, A.N., Lewandowski, F., Milligan, C., Spurlino, J.C., Abraham, W.M., Boswell-Smith, V., Page, C.P., Maryanoff, B.E.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-12-08
Resolution2.060
CATH Insert Date14 Dec, 2008

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Dec, 2008 Chopped
B 14 Dec, 2008 Chopped
C 14 Dec, 2008 Chopped
D 14 Dec, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2zecA01 16 Dec, 2008 2.40.10.10 Assigned
2zecA02 16 Dec, 2008 2.40.10.10 Assigned
2zecB01 16 Dec, 2008 2.40.10.10 Assigned
2zecB02 16 Dec, 2008 2.40.10.10 Assigned
2zecC01 16 Dec, 2008 2.40.10.10 Assigned
2zecC02 16 Dec, 2008 2.40.10.10 Assigned
2zecD01 16 Dec, 2008 2.40.10.10 Assigned
2zecD02 16 Dec, 2008 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
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