PDB 2zeb

PDB Information

PDB2ZEB
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives
Costanzo, M.J., Yabut, S.C., Zhang, H.-C., White, K.B., de Garavilla, L., Wang, Y., Minor, L.K., Tounge, B.A., Barnakov, A.N., Lewandowski, F., Milligan, C., Spurlino, J.C., Abraham, W.M., Boswell-Smith, V., Page, C.P., Maryanoff, B.E.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-12-08
Resolution2.500
CATH Insert Date14 Dec, 2008

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Dec, 2008 Chopped
B 14 Dec, 2008 Chopped
C 14 Dec, 2008 Chopped
D 14 Dec, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2zebA01 15 Dec, 2008 2.40.10.10 Assigned
2zebA02 15 Dec, 2008 2.40.10.10 Assigned
2zebB01 15 Dec, 2008 2.40.10.10 Assigned
2zebB02 15 Dec, 2008 2.40.10.10 Assigned
2zebC01 15 Dec, 2008 2.40.10.10 Assigned
2zebC02 15 Dec, 2008 2.40.10.10 Assigned
2zebD01 16 Dec, 2008 2.40.10.10 Assigned
2zebD02 16 Dec, 2008 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
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