PDB 2ze1

PDB Information

PDB2ZE1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets.
Cole, D.C., Stock, J.R., Chopra, R., Cowling, R., Ellingboe, J.W., Fan, K.Y., Harrison, B.L., Hu, Y., Jacobsen, S., Jennings, L.D., Jin, G., Lohse, P.A., Malamas, M.S., Manas, E.S., Moore, W.J., O'Donnell, M.M., Olland, A.M., Robichaud, A.J., Svenson, K., Wu, J., Wagner, E., Bard, J.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-12-05
Resolution2.200
CATH Insert Date14 Dec, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Dec, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2ze1A01 15 Dec, 2008 2.40.70.10 Assigned
2ze1A02 15 Dec, 2008 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1