PDB Information

PDB2YC0
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
Chowdhury, R., Yeoh, K.K., Tian, Y.M., Hillringhaus, L., Bagg, E.A., Rose, N.R., Leung, I.K., Li, X.S., Woon, E.C., Yang, M., McDonough, M.A., King, O.N., Clifton, I.J., Klose, R.J., Claridge, T.D., Ratcliffe, P.J., Schofield, C.J., Kawamura, A.
EMBO Rep.
HeaderOxidoreductase
Released2011-03-10
Resolution2.150
CATH Insert Date03 Apr, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 04 Apr, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2yc0A01 06 Apr, 2011 2.60.120.1660 Assigned
2yc0A02 06 Apr, 2011 1.10.287.1010 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9NWT6 HIF1N_HUMAN Homo sapiens Hypoxia-inducible factor 1-alpha inhibitor