PDB 2xx9

PDB Links
Overview

PDB Information

PDB	2XX9
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	RATTUS NORVEGICUS
Primary Citation	Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of Ampa Receptor Positive Allosteric Modulators. Ward, S.E., Harries, M., Aldegheri, L., Austin, N.E., Ballantine, S., Ballini, E., Bradley, D.M., Bax, B.D., Clarke, B.P., Harris, A.J., Harrison, S.A., Melarange, R.A., Mookherjee, C., Mosley, J., Dal Negro, G., Oliosi, B., Smith, K.J., Thewlis, K.M., Woollard, P.M., Yusaf, S.P. J.Med.Chem.
Header	Transport Protein
Released	2010-11-09
Resolution	1.970
CATH Insert Date	10 Apr, 2011

PDB Images (10)

Image of CATH 2xx9

2xx9

PDB 2xx9

Image of CATH 2xx9A

2xx9A

PDB Chain 2xx9A

Image of CATH 2xx9B

2xx9B

PDB Chain 2xx9B

Image of CATH 2xx9C

2xx9C

PDB Chain 2xx9C

Image of CATH 2xx9A01

2xx9A01

CATH Domain 2xx9A01

Image of CATH 2xx9A02

2xx9A02

CATH Domain 2xx9A02

Image of CATH 2xx9B01

2xx9B01

CATH Domain 2xx9B01

Image of CATH 2xx9B02

2xx9B02

CATH Domain 2xx9B02

Image of CATH 2xx9C01

2xx9C01

CATH Domain 2xx9C01

Image of CATH 2xx9C02

2xx9C02

CATH Domain 2xx9C02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2011	Chopped
B	11 Apr, 2011	Chopped
C	11 Apr, 2011	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2xx9A01	13 Apr, 2011	3.40.190.10	Assigned
2xx9A02	13 Apr, 2011	3.40.190.10	Assigned
2xx9B01	13 Apr, 2011	3.40.190.10	Assigned
2xx9B02	13 Apr, 2011	3.40.190.10	Assigned
2xx9C01	13 Apr, 2011	3.40.190.10	Assigned
2xx9C02	13 Apr, 2011	3.40.190.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2