PDB Information

PDB2XK6
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization.
Whelligan, D.K., Solanki, S., Taylor, D., Thomson, D.W., Cheung, K.M., Boxall, K., Mas-Droux, C., Barillari, C., Burns, S., Grummitt, C.G., Collins, I., Van Montfort, R.L., Aherne, G.W., Bayliss, R., Hoelder, S.
J.Med.Chem.
HeaderTransferase
Released2010-07-07
Resolution2.200
CATH Insert Date31 Oct, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 01 Nov, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2xk6A01 17 Feb, 2011 3.30.200.20 Assigned
2xk6A02 17 Feb, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P51955 NEK2_HUMAN Homo sapiens Serine/threonine-protein kinase Nek2