PDB 2x39

PDB Information

PDB2X39
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of 4-Amino-1-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Piperidine-4-Carboxamides as Selective, Orally Active Inhibitors of Protein Kinase B (Akt).
Mchardy, T., Caldwell, J.J., Cheung, K.M., Hunter, L.J., Taylor, K., Rowlands, M., Ruddle, R., Henley, A., De Haven Brandon, A., Valenti, M., Davies, T.G., Fazal, L., Seavers, L., Raynaud, F.I., Eccles, S.A., Aherne, G.W., Garrett, M.D., Collins, I.
J.Med.Chem.
HeaderTransferase
Released2010-01-22
Resolution1.930
CATH Insert Date25 Feb, 2010

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 26 Feb, 2010 Chopped
C 26 Feb, 2010 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2x39A01 02 Mar, 2010 3.30.200.20 Assigned
2x39A02 02 Mar, 2010 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P31751 AKT2_HUMAN Homo sapiens RAC-beta serine/threonine-protein kinase
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta