PDB 2x1n

PDB Information

PDB2X1N
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Design, Synthesis, and Evaluation of 2-Methyl- and 2-Amino-N-Aryl-4,5-Dihydrothiazolo[4,5-H]Quinazolin-8-Amines as Ring-Constrained 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Cyclin-Dependent Kinase Inhibitors.
Mcintyre, N.A., Mcinnes, C., Griffiths, G., Barnett, A.L., Kontopidis, G., Slawin, A.M.Z., Jackson, W., Thomas, M., Zheleva, D.I., Wang, S., Blake, D.G., Westwood, N.J., Fischer, P.M.
J.Med.Chem.
HeaderCell Cycle
Released2009-12-31
Resolution2.750
CATH Insert Date18 Feb, 2010

PDB Images (14)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 18 Feb, 2010 Chopped
B 18 Feb, 2010 Chopped
C 18 Feb, 2010 Chopped
D 18 Feb, 2010 Chopped
H 18 Feb, 2010 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2x1nA01 21 Feb, 2010 3.30.200.20 Assigned
2x1nA02 21 Feb, 2010 1.10.510.10 Assigned
2x1nB01 21 Feb, 2010 1.10.472.10 Assigned
2x1nB02 21 Feb, 2010 1.10.472.10 Assigned
2x1nC01 21 Feb, 2010 3.30.200.20 Assigned
2x1nC02 21 Feb, 2010 1.10.510.10 Assigned
2x1nD01 21 Feb, 2010 1.10.472.10 Assigned
2x1nD02 21 Feb, 2010 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2