PDB 2wxv

PDB Information

PDB2WXV
MethodX-RAY DIFFRACTION
Host OrganismTRICHOPLUSIA NI
Gene SourceHOMO SAPIENS
Primary Citation
Identification of Potent Pyrazolo[4,3-H]Quinazoline-3-Carboxamides as Multi-Cyclin-Dependent Kinase Inhibitors.
Traquandi, G., Ciomei, M., Ballinari, D., Casale, E., Colombo, N., Croci, V., Fiorentini, F., Isacchi, A., Longo, A., Mercurio, C., Panzeri, A., Pastori, W., Pevarello, P., Volpi, D., Roussel, P., Vulpetti, A., Brasca, M.G.
J.Med.Chem.
HeaderTransferase
Released2009-11-10
Resolution2.600
CATH Insert Date25 Feb, 2010

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 26 Feb, 2010 Chopped
B 26 Feb, 2010 Chopped
C 26 Feb, 2010 Chopped
D 26 Feb, 2010 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2wxvA01 02 Mar, 2010 3.30.200.20 Assigned
2wxvA02 02 Mar, 2010 1.10.510.10 Assigned
2wxvB01 02 Mar, 2010 1.10.472.10 Assigned
2wxvB02 02 Mar, 2010 1.10.472.10 Assigned
2wxvC01 02 Mar, 2010 3.30.200.20 Assigned
2wxvC02 02 Mar, 2010 1.10.510.10 Assigned
2wxvD01 02 Mar, 2010 1.10.472.10 Assigned
2wxvD02 02 Mar, 2010 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2