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PDB 2wpc

PDB Information

PDB2WPC
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA BRUCEI
Primary Citation
Dihydroquinazolines as a Novel Class of Trypanosoma Brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of Their Binding Mode by Protein Crystallography.
Patterson, S., Alphey, M.S., Jones, D.C., Shanks, E.J., Street, I.P., Frearson, J.A., Wyatt, P.G., Gilbert, I.H., Fairlamb, A.H.
J.Med.Chem.
HeaderOxidoreductase
Released2009-08-05
Resolution2.100
CATH Insert Date17 Oct, 2010

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 18 Oct, 2010 Chopped
B 18 Oct, 2010 Chopped
C 18 Oct, 2010 Chopped
D 18 Oct, 2010 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2wpcA01 17 Feb, 2011 3.50.50.60 Assigned
2wpcA02 17 Feb, 2011 3.50.50.60 Assigned
2wpcA03 17 Feb, 2011 3.30.390.30 Assigned
2wpcB01 17 Feb, 2011 3.50.50.60 Assigned
2wpcB02 17 Feb, 2011 3.50.50.60 Assigned
2wpcB03 17 Feb, 2011 3.30.390.30 Assigned
2wpcC01 17 Feb, 2011 3.50.50.60 Assigned
2wpcC02 17 Feb, 2011 3.50.50.60 Assigned
2wpcC03 17 Feb, 2011 3.30.390.30 Assigned
2wpcD01 17 Feb, 2011 3.50.50.60 Assigned
2wpcD02 17 Feb, 2011 3.50.50.60 Assigned
2wpcD03 17 Feb, 2011 3.30.390.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
Q389T8 Q389T8_TRYB2 Trypanosoma brucei brucei TREU927 Trypanothione reductase
CATH-Gene3D is a Global Biodata Core Resource Learn more...