PDB 2wkm

PDB Information

PDB2WKM
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Structure Based Drug Design of Crizotinib (Pf-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal-Epithelial Transition Factor (C-met) Kinase and Anaplastic Lymphoma Kinase (Alk).
Cui, J.J., Tran-Dube, M., Shen, H., Nambu, M., Kung, P.P., Pairish, M., Jia, L., Meng, J., Funk, L., Botrous, I., Mctigue, M., Grodsky, N., Ryan, K., Padrique, E., Alton, G., Timofeevski, S., Yamazaki, S., Li, Q., Zou, H., Christensen, J., Mroczkowski, B., Bender, S., Kania, R.S., Edwards, M.P.
J.Med.Chem
HeaderTransferase
Released2009-06-15
Resolution2.200
CATH Insert Date29 Aug, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 30 Aug, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2wkmA01 12 Sep, 2010 3.30.200.20 Assigned
2wkmA02 12 Sep, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor