PDB 2wez

PDB Information

PDB2WEZ
MethodX-RAY DIFFRACTION
Host OrganismCRICETULUS GRISEUS
Gene SourceHOMO SAPIENS
Primary Citation
Second Generation of Bace-1 Inhibitors. Part 1: The Need for Improved Pharmacokinetics.
Charrier, N., Clarke, B., Cutler, L., Demont, E., Dingwall, C., Dunsdon, R., Hawkins, J., Howes, C., Hubbard, J., Hussain, I., Maile, G., Matico, R., Mosley, J., Naylor, A., O'Brien, A., Redshaw, S., Rowland, P., Soleil, V., Smith, K.J., Sweitzer, S., Theobald, P., Vesey, D., Walter, D.S., Wayne, G.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2009-04-02
Resolution1.700
CATH Insert Date16 Aug, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2wezA01 25 Aug, 2009 2.40.70.10 Assigned
2wezA02 25 Aug, 2009 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1