PDB Information

PDB2W3I
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Exploration of 4,4-Disubstituted Pyrrolidine-1,2-Dicarboxamides as Potent, Orally Active Factor Xa Inhibitors with Extended Duration of Action.
Van Huis, C.A., Casimiro-Garcia, A., Bigge, C.F., Cody, W.L., Dudley, D.A., Filipski, K.J., Heemstra, R.J., Kohrt, J.T., Leadley, R.J.J., Narasimhan, L.S., Mcclanahan, T., Mochalkin, I., Pamment, M., Peterson, J.T., Sahasrabudhe, V., Schaum, R.P., Edmunds, J.J.
Bioorg.Med.Chem.
HeaderHydrolase
Released2008-11-12
Resolution1.900
CATH Insert Date16 Aug, 2009

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2w3iA01 21 Aug, 2009 2.40.10.10 Assigned
2w3iA02 21 Aug, 2009 2.40.10.10 Assigned
2w3iB00 21 Aug, 2009 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X