PDB Information

PDB2W2M
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants.
Bottomley, M.J., Cirillo, A., Orsatti, L., Ruggeri, L., Fisher, T.S., Santoro, J.C., Cummings, R.T., Cubbon, R.M., Lo Surdo, P., Calzetta, A., Noto, A., Baysarowich, J., Mattu, M., Talamo, F., De Francesco, R., Sparrow, C.P., Sitlani, A., Carfi, A.
J.Biol.Chem.
HeaderHydrolase/Receptor
Released2008-11-03
Resolution2.400
CATH Insert Date20 Nov, 2008

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 20 Nov, 2008 Chopped
E 20 Nov, 2008 Chopped
P 20 Nov, 2008 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2w2mA00 21 Nov, 2008 3.40.50.200 Assigned
2w2mE00 01 Jul, 2013 2.10.25.10 Assigned
2w2mP01 04 Feb, 2013 3.30.70.80 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
P01130 LDLR_HUMAN Homo sapiens Low-density lipoprotein receptor
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9