PDB 2w1i

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PDB Links
Overview

PDB Information

PDB	2W1I
Method	X-RAY DIFFRACTION
Host Organism	SPODOPTERA FRUGIPERDA
Gene Source	HOMO SAPIENS
Primary Citation	Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity. Howard, S., Berdini, V., Boulstridge, J.A., Carr, M.G., Cross, D.M., Curry, J., Devine, L.A., Early, T.R., Fazal, L., Gill, A.L., Heathcote, M., Maman, S., Matthews, J.E., Mcmenamin, R.L., Navarro, E.F., O'Brien, M.A., O'Reilly, M., Rees, D.C., Reule, M., Tisi, D., Williams, G., Vinkovic, M., Wyatt, P.G. J.Med.Chem.
Header	Transferase
Released	2008-10-17
Resolution	2.600
CATH Insert Date	29 Jan, 2009

PDB Images (7)

Image of CATH 2w1i

2w1i

PDB 2w1i

Image of CATH 2w1iA

2w1iA

PDB Chain 2w1iA

Image of CATH 2w1iB

2w1iB

PDB Chain 2w1iB

Image of CATH 2w1iA01

2w1iA01

CATH Domain 2w1iA01

Image of CATH 2w1iA02

2w1iA02

CATH Domain 2w1iA02

Image of CATH 2w1iB01

2w1iB01

CATH Domain 2w1iB01

Image of CATH 2w1iB02

2w1iB02

CATH Domain 2w1iB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jan, 2009	Chopped
B	29 Jan, 2009	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2w1iA01	19 Feb, 2009	3.30.200.20	Assigned
2w1iA02	19 Feb, 2009	1.10.510.10	Assigned
2w1iB01	19 Feb, 2009	3.30.200.20	Assigned
2w1iB02	19 Feb, 2009	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2