PDB 2vkm

PDB Information

PDB2VKM
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Potent Memapsin 2 (Beta-Secretase) Inhibitors: Design, Synthesis, Protein-Ligand X-Ray Structure, and in Vivo Evaluation.
Ghosh, A.K., Kumaragurubaran, N., Hong, L., Kulkarni, S., Xu, X., Miller, H.B., Reddy, D.S., Weerasena, V., Turner, R., Chang, W., Koelsch, G., Tang, J.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-12-04
Resolution2.050
CATH Insert Date18 Dec, 2008

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 18 Dec, 2008 Chopped
B 18 Dec, 2008 Chopped
C 18 Dec, 2008 Chopped
D 18 Dec, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2vkmA01 19 Dec, 2008 2.40.70.10 Assigned
2vkmA02 19 Dec, 2008 2.40.70.10 Assigned
2vkmB01 19 Dec, 2008 2.40.70.10 Assigned
2vkmB02 19 Dec, 2008 2.40.70.10 Assigned
2vkmC01 19 Dec, 2008 2.40.70.10 Assigned
2vkmC02 19 Dec, 2008 2.40.70.10 Assigned
2vkmD01 19 Dec, 2008 2.40.70.10 Assigned
2vkmD02 19 Dec, 2008 2.40.70.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1