PDB Information

PDB2TSR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug.
Sotelo-Mundo, R.R., Ciesla, J., Dzik, J.M., Rode, W., Maley, F., Maley, G.F., Hardy, L.W., Montfort, W.R.
Biochemistry
HeaderMethyltransferase
Released1998-06-19
Resolution2.600
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2tsrA00 05 Mar, 2006 3.30.572.10 Assigned
2tsrB00 05 Mar, 2006 3.30.572.10 Assigned
2tsrC00 05 Mar, 2006 3.30.572.10 Assigned
2tsrD00 05 Mar, 2006 3.30.572.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P45352 TYSY_RAT Rattus norvegicus Thymidylate synthase
P45352 TYSY_RAT Rattus norvegicus Thymidylate synthase
P45352 TYSY_RAT Rattus norvegicus Thymidylate synthase
P45352 TYSY_RAT Rattus norvegicus Thymidylate synthase