PDB 2rda
PDB Information
| PDB | 2RDA |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | The R163K mutant of human thymidylate synthase is stabilized in an active conformation: structural asymmetry and reactivity of cysteine 195.
Biochemistry
|
| Header | Transferase |
| Released | 2007-09-21 |
| Resolution | 2.670 |
| CATH Insert Date | 23 Jul, 2008 |
PDB Images (13)
2rda
PDB 2rda
2rdaA
PDB Chain 2rdaA
2rdaB
PDB Chain 2rdaB
2rdaC
PDB Chain 2rdaC
2rdaD
PDB Chain 2rdaD
2rdaE
PDB Chain 2rdaE
2rdaF
PDB Chain 2rdaF
2rdaA00
CATH Domain 2rdaA00
2rdaB00
CATH Domain 2rdaB00
2rdaC00
CATH Domain 2rdaC00
2rdaD00
CATH Domain 2rdaD00
2rdaE00
CATH Domain 2rdaE00
2rdaF00
CATH Domain 2rdaF00
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 24 Jul, 2008 | Chopped |
| B | 24 Jul, 2008 | Chopped |
| C | 24 Jul, 2008 | Chopped |
| D | 24 Jul, 2008 | Chopped |
| E | 24 Jul, 2008 | Chopped |
| F | 24 Jul, 2008 | Chopped |
CATH Domains (6)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 2rdaA00 | 26 Jul, 2008 | 3.30.572.10 | Assigned |
| 2rdaB00 | 26 Jul, 2008 | 3.30.572.10 | Assigned |
| 2rdaC00 | 26 Jul, 2008 | 3.30.572.10 | Assigned |
| 2rdaD00 | 26 Jul, 2008 | 3.30.572.10 | Assigned |
| 2rdaE00 | 25 Jul, 2008 | 3.30.572.10 | Assigned |
| 2rdaF00 | 26 Jul, 2008 | 3.30.572.10 | Assigned |
UniProtKB Entries (6)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
| P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |