PDB 2qk5

PDB Links
Overview

PDB Information

PDB	2QK5
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	Potent pyrrolidine- and piperidine-based BACE-1 inhibitors. Iserloh, U., Wu, Y., Cumming, J.N., Pan, J., Wang, L.Y., Stamford, A.W., Kennedy, M.E., Kuvelkar, R., Chen, X., Parker, E.M., Strickland, C., Voigt, J. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2007-07-10
Resolution	2.200
CATH Insert Date	13 Mar, 2008

PDB Images (7)

Image of CATH 2qk5

2qk5

PDB 2qk5

Image of CATH 2qk5A

2qk5A

PDB Chain 2qk5A

Image of CATH 2qk5B

2qk5B

PDB Chain 2qk5B

Image of CATH 2qk5A01

2qk5A01

CATH Domain 2qk5A01

Image of CATH 2qk5A02

2qk5A02

CATH Domain 2qk5A02

Image of CATH 2qk5B01

2qk5B01

CATH Domain 2qk5B01

Image of CATH 2qk5B02

2qk5B02

CATH Domain 2qk5B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	13 Mar, 2008	Chopped
B	13 Mar, 2008	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2qk5A01	14 Mar, 2008	2.40.70.10	Assigned
2qk5A02	14 Mar, 2008	2.40.70.10	Assigned
2qk5B01	14 Mar, 2008	2.40.70.10	Assigned
2qk5B02	14 Mar, 2008	2.40.70.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1