PDB 2pzy

PDB Information

PDB2PZY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
The discovery of carboline analogs as potent MAPKAP-K2 inhibitors
Wu, J.-P., Wang, J., Abeywardane, A., Andersen, D., Emmanuel, M., Gautschi, E., Goldberg, D.R., Kashem, M.A., Lukas, S., Mao, W., Martin, L., Morwick, T., Moss, N., Pargellis, C., Patel, U.R., Patnaude, L., Peet, G.W., Skow, D., Snow, R.J., Ward, Y., Werneburg, B., White, A.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-05-18
Resolution2.900
CATH Insert Date07 Nov, 2007

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped
B 08 Nov, 2007 Chopped
C 08 Nov, 2007 Chopped
D 08 Nov, 2007 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2pzyA01 10 Sep, 2008 3.30.200.20 Assigned
2pzyA02 10 Sep, 2008 1.10.510.10 Assigned
2pzyB01 08 Dec, 2008 3.30.200.20 Assigned
2pzyB02 08 Dec, 2008 1.10.510.10 Assigned
2pzyC01 08 Dec, 2008 3.30.200.20 Assigned
2pzyC02 08 Dec, 2008 1.10.510.10 Assigned
2pzyD01 08 Dec, 2008 3.30.200.20 Assigned
2pzyD02 08 Dec, 2008 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2