PDB 2p8s

PDB Links
Overview

PDB Information

PDB	2P8S
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin Biftu, T., Scapin, G., Singh, S., Feng, D., Becker, J.W., Eiermann, G., He, H., Lyons, K., Patel, S., Petrov, A., Sinha-Roy, R., Zhang, B., Wu, J., Zhang, X., Doss, G.A., Thornberry, N.A., Weber, A.E. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2007-03-23
Resolution	2.200
CATH Insert Date	24 May, 2007

PDB Images (7)

Image of CATH 2p8s

2p8s

PDB 2p8s

Image of CATH 2p8sA

2p8sA

PDB Chain 2p8sA

Image of CATH 2p8sB

2p8sB

PDB Chain 2p8sB

Image of CATH 2p8sA01

2p8sA01

CATH Domain 2p8sA01

Image of CATH 2p8sA02

2p8sA02

CATH Domain 2p8sA02

Image of CATH 2p8sB01

2p8sB01

CATH Domain 2p8sB01

Image of CATH 2p8sB02

2p8sB02

CATH Domain 2p8sB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	24 May, 2007	Chopped
B	24 May, 2007	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2p8sA01	16 Jul, 2007	3.40.50.1820	Assigned
2p8sA02	16 Jul, 2007	2.140.10.30	Assigned
2p8sB01	16 Jul, 2007	3.40.50.1820	Assigned
2p8sB02	16 Jul, 2007	2.140.10.30	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4