PDB 2p83

PDB Information

PDB2P83
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Potent and selective isophthalamide S(2) hydroxyethylamine inhibitors of BACE1.
Kortum, S.W., Benson, T.E., Bienkowski, M.J., Emmons, T.L., Prince, D.B., Paddock, D.J., Tomasselli, A.G., Moon, J.B., Laborde, A., Tenbrink, R.E.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-03-21
Resolution2.500
CATH Insert Date21 Jun, 2007

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 21 Jun, 2007 Chopped
B 21 Jun, 2007 Chopped
C 21 Jun, 2007 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
2p83A01 18 Jul, 2007 2.40.70.10 Assigned
2p83A02 18 Jul, 2007 2.40.70.10 Assigned
2p83B01 17 Jul, 2007 2.40.70.10 Assigned
2p83B02 17 Jul, 2007 2.40.70.10 Assigned
2p83C01 17 Jul, 2007 2.40.70.10 Assigned
2p83C02 17 Jul, 2007 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1