PDB 2p83

PDB Links
Overview

PDB Information

PDB	2P83
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Potent and selective isophthalamide S(2) hydroxyethylamine inhibitors of BACE1. Kortum, S.W., Benson, T.E., Bienkowski, M.J., Emmons, T.L., Prince, D.B., Paddock, D.J., Tomasselli, A.G., Moon, J.B., Laborde, A., Tenbrink, R.E. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2007-03-21
Resolution	2.500
CATH Insert Date	21 Jun, 2007

PDB Images (10)

Image of CATH 2p83

2p83

PDB 2p83

Image of CATH 2p83A

2p83A

PDB Chain 2p83A

Image of CATH 2p83B

2p83B

PDB Chain 2p83B

Image of CATH 2p83C

2p83C

PDB Chain 2p83C

Image of CATH 2p83A01

2p83A01

CATH Domain 2p83A01

Image of CATH 2p83A02

2p83A02

CATH Domain 2p83A02

Image of CATH 2p83B01

2p83B01

CATH Domain 2p83B01

Image of CATH 2p83B02

2p83B02

CATH Domain 2p83B02

Image of CATH 2p83C01

2p83C01

CATH Domain 2p83C01

Image of CATH 2p83C02

2p83C02

CATH Domain 2p83C02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	21 Jun, 2007	Chopped
B	21 Jun, 2007	Chopped
C	21 Jun, 2007	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2p83A01	18 Jul, 2007	2.40.70.10	Assigned
2p83A02	18 Jul, 2007	2.40.70.10	Assigned
2p83B01	17 Jul, 2007	2.40.70.10	Assigned
2p83B02	17 Jul, 2007	2.40.70.10	Assigned
2p83C01	17 Jul, 2007	2.40.70.10	Assigned
2p83C02	17 Jul, 2007	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1