PDB 2p4e

PDB Information

PDB2P4E
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia.
Cunningham, D., Danley, D.E., Geoghegan, K.F., Griffor, M.C., Hawkins, J.L., Subashi, T.A., Varghese, A.H., Ammirati, M.J., Culp, J.S., Hoth, L.R., Mansour, M.N., McGrath, K.M., Seddon, A.P., Shenolikar, S., Stutzman-Engwall, K.J., Warren, L.C., Xia, D., Qiu, X.
Nat.Struct.Mol.Biol.
HeaderHydrolase
Released2007-03-12
Resolution1.980
CATH Insert Date12 Apr, 2007

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 12 Apr, 2007 Chopped
P 12 Apr, 2007 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2p4eA01 09 Sep, 2013 3.40.50.200 Assigned
2p4eA02 09 Sep, 2013 2.60.120.690 Assigned
2p4eP01 04 Feb, 2013 3.30.70.80 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9